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Chemistry & Materials Forum No.153: The application of Mass spectrometry in antigen discovery for vaccine development (Dr. Jianjun Li)
发布时间:2019-10-31 浏览次数:

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Dr. Jianjun Li is a Senior Research Officer and Team Lead of Bioanalysis at Human Health Therapeutics of National Research Council (NRC-HHT). He was invited to have scientific exchange at our College of Chemical and Materials Science and gave a talk on 'Theapplication of Mass spectrometry in antigen discovery for vaccine development' at Academic Exchange Center onOct. 29th, 2019. It was hosted by prof. Xian Wang.

Dr. Li explained advantages of new tumor antigens, selection and preparation ofcandidate vaccines and how to carry out polysaccharide lipid research. Then he introduced the latest international progress and development trend of new tumor antigens and bacterial glycomics. Finally he focusedon application of mass spectrometry and capillary electrophoresis massspectrometry in tumor antigen, bacterial glycomics and lipids.

Dr. Li received his B. Sc. in Chemistry and Ph. D. in Analytical Chemistry at Wuhan University, in 1983 and 1993, respectively. Dr. Li’s research has involved the development of high-resolution separation techniques coupled with mass spectrometry and their applications to the structural characterization of various biologically molecules. From 1997 to 2001, he focused on the development of chip-based capillary electrophoresis-mass spectrometry systems. His current research interest is method development and application forbacterial vaccine and cancer vaccine, including the structure and biosynthesis of bacterial surface carbohydrates and cancer neoantigen presented by major histocompatibilitycomplex (MHC). He is author or co-author of over 200 original peer-reviewed scientific papers, 8 book chapters and edits the book entitled Methods in Functional Glycomics.


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